Nodular Subcutaneous Phaeohyphomycosis due to Medicopsis romeroi in an Immunocompetent Patient
Published: August 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/50213.15244
Smita Deshkar, Niranjan Patil, Ashish Lad, Shraddha Amberkar, Swati Sharan
1. Microbiologist, Department of Microbiology and Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.
2. Head, Department of Microbiology and Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.
3. Senior Laboratory Manager, Department of Microbiology and Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.
4. Section Head, Department of Microbiology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.
5. Senior Scientific Officer, Department of Molecular Biology, Metropolis Healthcare Limited, Mumbai, Maharashtra, India.
Correspondence
Dr. Smita Deshkar,
Metropolis Healthcare Limited, Kohinoor City, Commercial Bldg-A, 4th Floor,
Off-L.B.S Road, Vidyavihar (West), Mumbai-400070, Maharashtra, India.
E-mail: smitadeshkar@ymail.com
Fungal infections like subcutaneous phaeohyphomycosis are uncommon but are increasing lately, especially in tropical regions like India. Identification of correct aetiologic agent is essential as different species can have different organ tropism. Here, a rare case of nodular subcutaneous phaeohyphomycosis in an immunocompetent 62-year-old male patient who developed nodule over right dorsum of foot is reported. After various diagnostic tests a rare dematiaceous fungus Medicopsis romeroi was identified as a causative agent in the nodular material by Internal Transcribed Spacer (ITS) sequencing. Surgical excision and antifungal therapy of itraconazole proved beneficial with no recurrence during a six months of follow-up. Medicopsis romeroi has been debated for its role in human infections however, it should be considered as one of the aetiologic agents of subcutaneous phaeohyphomycosis.
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